ASEA Testimonials and Science

ASEA users report positive experiences after using the product.  These testimonials are followed by research studies that explain why the product is effective. 

ASEA (the company):  "ASEA (also called ASEA water by some people) is trillions of stable, perfectly balanced Redox Signaling Molecules suspended in a pristine saline solution—the same molecules that exist in the cells of the human body.  Redox Signaling is a function that is central to all life on the planet. Redox Signaling molecules are created within every cell of the body and are vital to the immune system and to cellular healing mechanisms. They are so essential to life that without them, you would die within seconds. A proper supply of Redox Signaling molecules enables cellular healing: damaged, dysfunctional cells fading away and healthy, vibrant cells taking over. Redox Signaling molecules are vital for the health of your cells; that’s why your body makes its own supply. But after the age of 12, our cells make fewer and fewer of these molecules. ASEA is the world’s only source for replenishing Redox Signaling molecules.  ASEA is the first and only stable, perfectly balanced mixture of these Redox Signaling reactive molecules that exists outside of living cells, and can be used to help maintain proper balance inside the body to support the immune system and healing process."  Although not advertised as a Nrf2 activator, the research clearly states that it does activate Nrf2, and increases glutathione production 500%.  There have been numerous scientific studies on this product.  See asea.net.

Joe:  Since starting on ASEA, I have more energy and mental clarity than I’ve ever had. My sleep is much deeper. During workouts, I have more endurance, more flexibility, and quicker recovery with ASEA.  I believe in ASEA because of the results I feel as well as all of my friends and family’s experiences.  I’ve just never had such a good feeling about a company before.  http://discoverredoxsignalingmolecules.com/testimonials/
  

James Lawrence:  A friend introduced me to ASEA and I wasn’t sure what to think. I went to a sports clinic and got tested and then went on the product for 6 weeks.  I returned and did the same test.  I was able to run faster, on a steeper incline, with a lower heart rate.  Tests don’t lie and so I knew that ASEA was something that I had to have to help me accomplish my goals.  http://discoverredoxsignalingmolecules.com/testimonials/

 

 

Cody Waite:  My body takes a beating as an Xterra off-road triathlete.  Typical distances are about a one mile swim, 20 mile off-road mountain bike, and a typical race is usually about six miles.  The off-road component makes it quite challenging.  I believe ASEA has helped me to achieve a higher level of athletic performance.  If my body is working properly at the cellular level everything is coming together.  http://discoverredoxsignalingmolecules.com/testimonials/

 

Rich Roll:  I am a big fan of ASEA, and feel it has significantly contributed to the advancement of not only my training and athletic performance, but also my overall wellness, as well as that of my wife.  http://discoverredoxsignalingmolecules.com/testimonials/

 

 

Sinjin Smith:  Beach volleyball is a very difficult sport.  It requires a lot from your body to move around and cover the court.  ASEA allows me to actually go out and train, feel good, recover, and then train more often.  Now I tell everyone I know about ASEA because I have never seen anything like it.  http://discoverredoxsignalingmolecules.com/testimonials/

 

Craig Stanton:  At first glance, being a race car driver might not seem like it requires much athletic ability.  But believe me it’s not as easy as it looks.  I race just under 300 days a year.  We go 2Gs when braking and 3-4 Gs when turning – all in a super heated car, which inside is about 125 degrees. To get ready for races I train like a tri-athlete. In fact, I train non-stop.  I’ve learned that when you push your body to its physical limits you need proper nutrition and supplements.  I need the right supplements to help with my cardiovascular strength and to properly recover.  That’s where ASEA comes in.  ASEA really helps with my focus, balance and recovery times.  http://discoverredoxsignalingmolecules.com/testimonials/

 

Sharolyn:  I was at the end of my rope and very unhappy because I was having to rest quite a bit  throughout the day.  Then I found ASEA.  Within a week of drinking ASEA, I felt like I had my life back. I could be a mom and a wife again!  http://discoverredoxsignalingmolecules.com/testimonials/

 

Jan:  I am a stay-at-home mom with 7 children ages 17-22.  In my first of taking ASEA I saw a big increase in my energy level.  Additionally, as soon as I go to bed I go right to sleep.  I feel ASEA is the best product I have ever used.  http://discoverredoxsignalingmolecules.com/testimonials/


 Will:  I have so much more energy now. Anyone who wants to get more out of their day and have more energy in the process should drink ASEA. I simply believe that ASEA gets my body organized, from the inside, so it wants to function better.  http://discoverredoxsignalingmolecules.com/testimonials/

 

Patricia:  After taking ASEA I started sleeping deeper at night.  Just the other night I told my husband, “I sleep like I did when I was four years old,” and sleep is such a blessing.  http://discoverredoxsignalingmolecules.com/testimonials/

 

Yvette:  Since I’ve started taking ASEA I’ve had so much more energy.  Running on a treadmill—usually I’m able to do a mile and a half, but now I’m able to do two miles without any problem, no soreness, and I’m so full of energy after I’ve finished the workout.  That’s amazing!  http://discoverredoxsignalingmolecules.com/testimonials/

 

Cindy:  I have been using ASEA around 2 months now. In those 2 months my energy level has literally jumped to where I never thought it would be again. Since drinking ASEA I have been healthier, and my drive and get up and go are at a 10. Your never realize you were at a 5 until you get back to 10.  ASEA has changed my life.  http://discoverredoxsignalingmolecules.com/testimonials/

Report for ASEA on Experimental Results – In Vitro Antioxidant Enhancement and Oxidative Stress Reduction 2009

 Purpose:

This document reports to ASEA the results of the in vitro tests run from February to March, 2009. Live cells in culture dishes were exposed to ASEA and the bioactivity regarding antioxidant activity of Glutathione Peroxidase (GPx) and Superoxide Dismutase (SOD) as well as the increase in the native production of these antioxidants inside cells was measured. In addition, tests were run to determine if oxidative stress was reduced in the cells and that cell viability was enhanced by exposure to ASEA.

Experimental Methods for Antioxidant Activity:

Cells were cultured in several dishes with a bovine serum growth medium. As a primary measure, mouse epithelial-like cells were cultured (these cells react similarly to human cells) and later human endothelial cells were used to obtain relevant quantitative results.   In the antioxidant enhancement tests, some of the cell cultures were exposed to ASEA and others cultures to the same amount of an inert phosphate buffered saline solution (PBS). The antioxidant activity of the cells in each was measured by a purchased kit, Array Design Stressgen kit (#900-158 for GPx activity and #900-157 for SOD activity). The chemical reagents inside these kits measure the ability of the antioxidants in the cell extracts to reduce oxidant activity that occurs naturally when certain oxidizing biological chemicals are added.   Due to the fact that some of the reactive molecules in ASEA might react and interfere with some of the chemical agents in these kits, several preliminary experiments were done to examine the accuracy of the results based against known standards of antioxidant activity and adjustments were made.

 Results of Antioxidant Activity Tests:

The first results obtained showed large, well-defined effects. The cell extracts exposed to ASEA exhibited eight (8) times the antioxidant efficiency for GPx than those exposed to the inert PBS. The SOD antioxidant efficiency was slightly less, with about 5 times enhancements in efficiency. Of note, this efficiency was evident especially at low level concentrations of ASEA, tested down to 2.5% of full strength. Increasing the concentration of ASEA at high concentrations did not notably increase the antioxidant efficiency; thus there appears to be a very low saturation threshold at low concentrations of GPx. More experimentation would need to be done at very low concentrations of ASEA in order to understand the concentration dependence fully.   It is safe to say that at least a 500% improvement in the overall antioxidant efficiency was seen during these preliminary in vitro tests due to ASEA exposure.

Experimental Methods for Antioxidant Up-regulation:

In these experiments, some cultured human endothelial cells were exposed to ASEA and others only to an inert phosphate buffer solution (PBS). Standard Western Blot analysis on all cells was done to determine if exposure to ASEA activated the nucleus to call for increased production of antioxidants, such as GPx. The concentrations of transcription factors (messengers) in the nucleus that call for up-regulation of antioxidants were also measured in human endothelial cells and compared to cells that had not been exposed to ASEA.   The movement of the transcription factors into the nucleus can be seen with certain dyes under a microscope and thus offers a way to see the call for up-regulation of antioxidants without some of the obstacles presented by the use of endothelial cells.   Since the production of antioxidants can also be up-regulated by exposure of the cells to certain low levels of inflammatory toxins, tests were done to make sure that ASEA was not provoking the cells to undergo this low-level inflammatory or toxic response.

Results for Antioxidant Up-Regulation

The results for these tests were extraordinary in several regards. First, there was a real up-regulation of anti-oxidant production in cells exposed to ASEA. This effect was temporary, lasting only about 120 minutes but was clearly visible. The most interesting result, however, is that exposure to ASEA at any concentration did not invoke the normal inflammatory transcription factor (NF-kappaB) and yet did invoke the antioxidant transcription factor (NRF2). Stimulating the production of antioxidants without stimulation of low-level inflammation is very rare and has stirred some interest in the scientific community.   The tests that measured the movement of transcription factors were controlled tests, they had “positive controls” that showed the test was working. For example, a small amount of a toxin that is known to cause the inflammatory response (movement of the NF-kappaB transcription factor) was tested side by side with the ASEA, a positive response was very clearly seen with the toxin and no response was seen with ASEA. With the antioxidant up-regulation transcription factor NRF2, positive movement of this transcription factor was seen in both ASEA and in the positive control. Hundreds of cells were observed in order to obtain these results.   These results were also verified by the Western Blot analysis showing clear responses in the increase of antioxidants upon exposure to ASEA relative to the saline control.   

[INTERPRETATION:  Experiments done on ASEA showed that Glutathione was 8 times more efficient, and that Superoxide Dismutase was 5 times more efficient, especially at lower doses.  ASEA improved the cell’s overall antioxidant efficiency by at least 500%.  ASEA did not start the inflammation factors that usually cause Nrf2 activation, but rather activated Nrf2 without it.  ASEA clearly activates Nrf2, which increases natural antioxidants.] 

(see the full report at http://myaseaonline.info/asea.net/USEnglish/ASEA_Antioxidant_Efficiency_US_ENG.pdf) 



White Paper on the Effect of an Immune-Supporting Supplement, ASEA, on Athletic Performance based on a Pilot VO2max Test June 15, 2010

 Principal Investigator: Gary L. Samuelson, Ph.D. Independent Science Advisor

Study Conclusions

Ingestion of the test supplement, ASEA™, for 7-10 days prior to and immediately before a VO2max test, was shown to significantly increase the time it took for 70% of the participants to reach VO2max under equivalent carefully regulated power ramp-up conditions. Time to VT likewise was significantly extended.

The extension of time to reach VT, under similar increasing demands for energy, is a direct indication that the aerobic phase of metabolism is being extended and/or the anaerobic phases somehow are being delayed as the demand for energy increases.

The lack of any other changes in the physiological parameters (VO2max, VT, AeT, AT and associated heart rates) suggests that cardiovascular capacity, lung capacity and blood oxygen capacity and regulation are not affected. This assumption is reasonable, given that the short duration of this study excluded the possibility of training effects.

One feasible explanation for the results lies in the enhancement of aerobic efficiencies, meaning that more aerobic energy can be extracted at the same physiological state, or that the clearance of lactates or CO2 becomes more efficient, again allowing greater aerobic efficiency. Note that “time to AeT” and “time to AT” were not compiled in this study, however changes in these parameters would be expected and might offer clues to determine the underlying mechanisms.  The results of this pilot test indicate that there is a strong case for athletic performance enhancement and further investigation is warranted. A placebo-based double-blind test, measuring the more subtle effects in ventilation and heart rates along with increases in blood lactate levels during a controlled, calibrated power ramp would provide defensible evidence for this effect and better support for some specific underlying mechanisms of action.  (see the full study at http://myaseaonline.info/asea.net/USEnglish/WhitePaperVTUSENG.pdf)

[INTERPRETATION:  Athletes who took ASEA lasted much longer on endurance tests.  As their need for energy increased, their cells still had plenty of oxygen to keep up with the demand.  In fact, they had more energy than usual in the same physical conditions.  ASEA can be a great athletic performance enhancer.]


RESEARCH:  Here is another scientific study about ASEA reported in June 2010.  It is too long to include all of the information here, but it discusses the tests and results that ASEA has on activation of Nrf2 and the increased production of Glutathione, Superoxide Dismutase, and other body-produced antioxidants that protect the body, without stimulating any oxidative stress in order to do it.  Bioactivity of ASEA Related to Toxicity, Glutathione Peroxidase, Superoxide Dismutase Efficacy and Related Transcription Factors